The difference between the words "Loose" and "Lose" is in both the length of the vowel, and the sound made by S. In "loose", S is voiceless, while "lose" makes S sound like Z.
Listen along and improve your own ability to lengthen your vowel sounds, and change S to Z sounds.
If you're looking for more material on this topic, check the links below to keep things moving forward!
Check out my video course on Udemy to kick-start your AccenTraining Journey!
https://www.udemy.com/course/command-the-american-accents-rhythm-and-pronunciation/?referralCode=C96318A268600601A20F
Stretching Vowel Sounds
https://accentrainingclub.buzzsprout.com/1316983/8785607-067-stretching-vowel-sounds
S as Z Word Endings
https://accentrainingclub.buzzsprout.com/1316983/7506310-026-when-s-endings-sound-like-z
Es as Iz Word Endings
https://accentrainingclub.buzzsprout.com/1316983/10752305-118-voice-es-word-endings-to-sound-like-iz
S as Z midword
https://accentrainingclub.buzzsprout.com/1316983/10629646-116-5-words-with-s-sounding-like-z